Methods:

36 intrabony defects in 36 individual patients were treated with either demineralized freeze-dried bone allograft (DFDBA) or platelet-rich fibrin (PRF).  Data was collected at baseline and at 6 month follow up and included radiographic bone fill and changes in clinical attachment levels (CAL).

Results:

Both treatment groups had significant gain in clinical attachment levels and bone fill, with no significant difference between groups.  Mean CAL gain for DFDBA was 1.16 ± 1.33 mm and mean radiographic bone fill was 1.14 ± 0.88 mm.  PRF had a mean CAL gain of 1.03 ± 0.86 and mean radiographic bone fill of 1.10 ± 1.01 mm.

Conclusions:

Intrabony defects treated with either DFDBA or PRF had a significant gain in CAL as well as bone fill after 6 months of healing and there was no significant difference between the two materials.

For more information please refer to:

Journal of Periodontology, November 2016, Vol. 87, No. 11

Clinical and Radiographic Evaluation of Demineralized Freeze-Dried Bone Allograft Versus Platelet-Rich Fibrin for the Treatment of Periodontal Intrabony Defects in Humans

Jane K. Chadwick, Michael P. Mills,  and Brian L. Mealey